產品詳情
簡單介紹:
2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody
詳情介紹:
OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
Research Articles on 2'-5'-Oligoadenylate Synthetase 1 (OAS1)
Target | 2'-5'-Oligoadenylate Synthetase 1 (OAS1) |
Clonality | Polyclonal |
Reactivity | Human, Mouse |
Tested Applications | ELISA, WB, IHC |
Host | Rabbit |
Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | KLH-conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human OAS1. |
Isotype | IgG |
Form | Liquid |
Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P00973 (UniProt, ExPASy) |
UniProt Entry Name | OAS1_HUMAN |
NCBI Accession | NP_001027581.1 NP_002525.2 NP_058132.2 |
KEGG | hsa:4938 |
String | 9606.ENSP00000388001 |
Molecular Weight | Calculated MW: 46 kDa |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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