產品詳情
簡單介紹:
26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5) Antibody
詳情介紹:
Proteasome 26S Subunit, Non ATPase 5 Antibody is a Rabbit Polyclonal against Proteasome 26S Subunit, Non ATPase 5. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5)
Target | 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5) |
Clonality | Polyclonal |
Reactivity | Human |
Tested Applications | WB, IHC, IF/ICC |
Host | Rabbit |
Recommended dilutions | WB: 1-5 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | PSMD5 (Lys143-Arg341) |
Form | Liquid |
Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | Q16401 (UniProt, ExPASy) |
UniProt Secondary AC | B4DZM8, Q15045, Q4VXG8 |
UniProt Entry Name | PSMD5_HUMAN |
Gene Symbol | PSMD5 |
GeneID | 5711 |
OMIM | 604452 |
NCBI Accession | NP_001257356.1 NM_001270427.1 NP_005038.1 NM_005047.3 |
HGNC | 9563 |
KEGG | hsa:5711 |
Ensembl | ENSG00000095261 |
String | 9606.ENSP00000210313 |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Note | This product is for research use only. |
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