產品詳情
簡單介紹:
3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) Antibody
詳情介紹:
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Research Articles on 3(2),5-Bisphosphate Nucleotidase 1 (BPNT1)
Target | 3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) |
Clonality | Polyclonal |
Reactivity | Human |
Tested Applications | ELISA, WB |
Host | Rabbit |
Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | KLH-conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1. |
Isotype | IgG |
Form | Liquid |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | O95861 (UniProt, ExPASy) |
UniProt Secondary AC | A8K7C8, B4DPS5, B4DUS9, D3DTA9, Q8WVL5, Q9UGJ3 |
UniProt Entry Name | BPNT1_HUMAN |
Gene Symbol | BPNT1 |
KEGG | hsa:10380 |
String | 9606.ENSP00000446828 |
Molecular Weight | Calculated MW: 33.4 kDa |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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