產品詳情
簡單介紹:
3-Galactosyl-N-Acetylglucosaminide 4-Alpha-L-Fucosyltransferase FUT3 (FUT3) Antibody
詳情介紹:
FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosesynthesis. It encodes an enzyme with alpha (1, 3) fucosyltransferase and alpha (1, 4) fucosyltransferase activities.
Research Articles on 3-Galactosyl-N-Acetylglucosaminide 4-Alpha-L-Fucosyltransferase FUT3 (FUT3)
Target | 3-Galactosyl-N-Acetylglucosaminide 4-Alpha-L-Fucosyltransferase FUT3 (FUT3) |
Clonality | Polyclonal |
Reactivity | Human |
Tested Applications | ELISA, WB |
Host | Rabbit |
Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | KLH-conjugated synthetic peptide between 288-315 amino acids from the C-terminal region of human FUT3. |
Isotype | IgG |
Form | Liquid |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P21217 (UniProt, ExPASy) |
UniProt Secondary AC | B5U7U9, B5U7V0, Q32NE7, Q99448, Q99449 |
UniProt Entry Name | FUT3_HUMAN |
Gene Symbol | FUT3 |
GeneID | 2525 |
OMIM | 111100 |
HGNC | 4014 |
KEGG | hsa:2525 |
Ensembl | ENSG00000171124 |
String | 9606.ENSP00000305603 |
Molecular Weight | Calculated MW: 42.1 kDa |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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