產品詳情
簡單介紹：
ARF GTPase Activating Protein GIT1 (GIT1) Antibody
詳情介紹：
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodsia.
Research Articles on ARF GTPase Activating Protein GIT1 (GIT1)
| Target | ARF GTPase Activating Protein GIT1 (GIT1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 487-517 amino acids from human GIT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y2X7 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DGU9, B4DSV3, Q86SS0, Q9BRJ4 |
| UniProt Entry Name | GIT1_HUMAN |
| String | 9606.ENSP00000378338 |
| Molecular Weight | Calculated MW: 84.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat GIT1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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