产品名称：ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Antibody

ARFGAP1 is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine.

Target	ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 377-406 amino acids from the C-terminal region of human ARFGAP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8N6T3 (UniProt, ExPASy)
UniProt Entry Name	ARFG1_HUMAN
NCBI Accession	NP_001268411.1 NP_001268412.1 NP_001268413.1 NP_060679.1 NP_783202.1
KEGG	hsa:55738
String	9606.ENSP00000314615
Molecular Weight	Calculated MW: 44.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1)