產品名稱：Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody

AGER Antibody is a Rabbit Polyclonal antibody against AGER. The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).

Target	Advanced Glycosylation End Product-Specific Receptor (AGER)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 30-330 of human AGER.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15109 (UniProt, ExPASy)
UniProt Entry Name	RAGE_HUMAN
Gene Symbol	AGER
GeneID	177
NCBI Accession	NP_001127.1
KEGG	hsa:177
String	9606.ENSP00000364210
Molecular Weight	Calculated MW: 43 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Advanced Glycosylation End Product-Specific Receptor (AGER)