產品詳情
簡單介紹:
Aflibercept
詳情介紹:
Aflibercept is a recombinant fusion protein biosesimilar expressed in CHO cells, targeting VEGFA, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Aflibercept is a manufactured protein that acts as a decoy receptor for all VEGF-A isoforms and placental growth factor. This agent was engineered through fusion of the ligand-binding domains from two VEGF receptors with the constant region of IgG1, resulting in high-affinity VEGF binding and prevention of VEGF pathway activation.
Research Articles on VEGFA
Target | VEGFA |
Clonality | Monoclonal |
Reactivity | Human |
Expression | Recombinant |
Tested Applications | ELISA, WB |
Host | Human |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Isotype | IgG1 |
Form | Liquid |
Purity | > 95% |
Purification | Purified from cell culture supernatants by Protein A/G chromatography. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Buffer | 0.01 M PBS. pH 7.4. |
CAS Number | 862111-32-8 |
Concentration | Batch-dependent, typically between 0.5-2.0 mg/ml. |
Availability | Shipped within 7-12 working days. |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
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