產品名稱：Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) Antibody

Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) Antibody is a Rabbit Polyclonal antibody for the detection of AKR1C2.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Target	Aldo-Keto Reductase Family 1 Member C2 (AKR1C2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Aldo-keto reductase family 1 member C2
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P52895 (UniProt, ExPASy)
UniProt Secondary AC	A8K2N9, B4DKR9, Q14133, Q5SR16, Q7M4N1, Q96A71
UniProt Entry Name	AK1C2_HUMAN
Gene Symbol	AKR1C2
GeneID	1646
OMIM	600450
HGNC	385
KEGG	hsa:1646
Ensembl	ENSG00000151632
String	9606.ENSP00000370129
Enzyme Commission Number	EC 1.-.-.- EC 1.1.1.213 EC 1.3.1.20
Molecular Weight	Observed MW: 37 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Aldo-Keto Reductase Family 1 Member C2 (AKR1C2)