產品詳情
簡單介紹：
Alpha-2-Macroglobulin (A2M) Antibody
詳情介紹：
A2M Antibody is a Rabbit Polyclonal antibody against A2M. Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008].
Research Articles on Alpha-2-Macroglobulin (A2M)
| Target | Alpha-2-Macroglobulin (A2M) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1155-1474 of human Alpha-2-Macroglobulin (A2M). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01023 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97 |
| UniProt Entry Name | A2MG_HUMAN |
| Gene Symbol | A2M |
| GeneID | 2 |
| NCBI Accession | NP_000005.2 |
| KEGG | hsa:2 |
| String | 9606.ENSP00000323929 |
| Molecular Weight | Calculated MW: 163 kDa Observed MW: 163 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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