產品詳情
簡單介紹：
Alpha-2-Macroglobulin (A2M) Antibody
詳情介紹：
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Research Articles on Alpha-2-Macroglobulin (A2M)
| Target | Alpha-2-Macroglobulin (A2M) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1162-1192 amino acids from the C-terminal region of human A2M. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01023 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97 |
| UniProt Entry Name | A2MG_HUMAN |
| Gene Symbol | A2M |
| KEGG | hsa:2 |
| String | 9606.ENSP00000323929 |
| Molecular Weight | Calculated MW: 163 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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