產品詳情
簡單介紹：
Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) Antibody
詳情介紹：
Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2, 6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).
Research Articles on Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 (ST6GALNAC1)
| Target | Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human ST6GALNAC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NSC7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6UW90, Q9NSC6 |
| UniProt Entry Name | SIA7A_HUMAN |
| Gene Symbol | ST6GALNAC1 |
| String | 9606.ENSP00000156626 |
| Molecular Weight | Calculated MW: 68.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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