產品詳情
簡單介紹:
Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody
詳情介紹:
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been sociated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.
Research Articles on Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A)
Target | Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) |
Clonality | Polyclonal |
Reactivity | Human |
Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
Host | Rabbit |
Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | KLH-conjugated synthetic peptide between 365-391 amino acids from the Central region of human SCNN1A. |
Isotype | IgG |
Form | Liquid |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P37088 (UniProt, ExPASy) |
UniProt Secondary AC | A5X2U9, B4E2Q5, C5HTZ0, O43271, Q6GSQ6, Q9UM64 |
UniProt Entry Name | SCNNA_HUMAN |
Gene Symbol | SCNN1A |
KEGG | hsa:6337 |
String | 9606.ENSP00000353292 |
Molecular Weight | Calculated MW: 75.7 kDa |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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