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Anti-FLRT2 antibody (300-400) (STJ119717) STJ119717|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情
  • 產品名稱:Anti-FLRT2 antibody (300-400) (STJ119717)

  • 產品型號:STJ119717
  • 產品廠商:ST john's laboratory
  • 產品文檔:
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簡單介紹:
Anti-FLRT2 antibody (300-400) (STJ119717)
詳情介紹:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FLRT2 (300-400) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FLRT2
Gene ID: 23768
Uniprot ID: FLRT2_HUMAN
Immunogen Region: 300-400
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1).
Immunogen Sequence: SNLKQLTARNNPWFCDCSIK WVTEWLKYIPSSLNVRGFMC QGPEQVRGMAVRELNMNLLS CPTTTPGLPLFTPAPSTASP TTQPPTLSIPNPSRSYTPPT P
Tissue Specificity Expressed in pancreas, skeletal muscle, brain, and heart.
Post Translational Modifications N-glycosylated. Proteolytic cleavage in the juxtamembrane region gives rise to a soluble ectodomain. Cleavage is probably effected by a metalloprotease.
Function Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
Protein Name Leucine-Rich Repeat Transmembrane Protein Flrt2
Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2
Database Links Reactome: R-HSA-5654687
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Endoplasmic Reticulum Membrane
Cell Junction
Focal Adhesion
Secreted
Extracellular Space
Extracellular Matrix
Microsome Membrane
Synapse
Synaptosome
Proteolytic Cleavage Gives Rise To A Shedded Ectodomain
Alternative Antibody Names Anti-Leucine-Rich Repeat Transmembrane Protein Flrt2 antibody
Anti-Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2 antibody
Anti-FLRT2 antibody
Anti-KIAA0405 antibody
Anti-UNQ232 antibody
Anti-PRO265 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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