產品詳情
簡單介紹：
Anti-CDT1/Dup antibody (C-Term) (STJ70239)
詳情介紹：
| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-CDT1/Dup (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | WB-1-3µg/ml ELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CDT1 |
| Gene ID: | 81620 |
| Uniprot ID: | CDT1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_112190.2 |
| Immunogen Sequence: | ARLAHQTRAEEGL |
| Function | Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene. |
| Protein Name | Dna Replication Factor Cdt1 Double Parked Homolog Dup |
| Database Links | Reactome: R-HSA-68867 Reactome: R-HSA-68949 Reactome: R-HSA-68962 Reactome: R-HSA-69052 Reactome: R-HSA-69205 |
| Cellular Localisation | Nucleus Chromosome Centromere Kinetochore Transiently Localizes To Kinetochores During Prometaphase And Metaphase |
| Alternative Antibody Names | Anti-Dna Replication Factor Cdt1 antibody Anti-Double Parked Homolog antibody Anti-Dup antibody Anti-CDT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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