產品詳情
簡單介紹:
Anti-14-3-3 Beta/Zeta antibody (151-200 aa) (STJ91368)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-14-3-3 protein zeta/delta and 14-3-3 protein beta/alpha (151-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 ELISA 1:20000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | YWHAZ YWHAB |
Gene ID: | 7534 7529 |
Uniprot ID: | 1433Z_HUMAN 1433B_HUMAN |
Immunogen Region: | 151-200 aa |
Specificity: | 14-3-3 Beta/Zeta Polyclonal Antibody detects endogenous levels of 14-3-3 Beta/Zeta protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human YWHAZ at the amino acid range 151-200 |
Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodsia and membrane ruffle formation. In neurons, regulates spine maturation through the modulation of ARHGEF7 activity. |
Protein Name | 14-3-3 Protein Zeta/Delta Protein Kinase C Inhibitor Protein 1 Kcip-1 |
Database Links | Reactome: R-HSA-111447 Reactome: R-HSA-1445148 Reactome: R-HSA-3769402 Reactome: R-HSA-392517 Reactome: R-HSA-430116 Reactome: R-HSA-450604 Reactome: R-HSA-512988 Reactome: R-HSA-5625740 Reactome: R-HSA-5628897 Reactome: R-HSA-75035 Reactome: R-HSA-9013700 Reactome: R-HSA-9604323 Reactome: R-HSA-9614399 |
Cellular Localisation | Cytoplasm Melanosome Located To Stage I To Stage Iv Melanosomes |
Alternative Antibody Names | Anti-14-3-3 Protein Zeta/Delta antibody Anti-Protein Kinase C Inhibitor Protein 1 antibody Anti-Kcip-1 antibody Anti-YWHAZ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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