產品詳情
簡單介紹:
Anti-A Cyclase V/VI antibody (931-980 aa) (STJ91397)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Adenylate cyclase type 5 and Adenylate cyclase type 6 (931-980 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADCY6 ADCY5 |
Gene ID: | 112 111 |
Uniprot ID: | ADCY6_HUMAN ADCY5_HUMAN |
Immunogen Region: | 931-980 aa |
Specificity: | A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human ADCY5/6 at the amino acid range 931-980 |
Post Translational Modifications | Phosphorylated by RAF1. |
Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. |
Protein Name | Adenylate Cyclase Type 5 Atp Pyrophosphate-Lyase 5 Adenylate Cyclase Type V Adenylyl Cyclase 5 Ac5 |
Database Links | Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-381676 Reactome: R-HSA-400042 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-5610787 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cell Projection Cilium |
Alternative Antibody Names | Anti-Adenylate Cyclase Type 5 antibody Anti-Atp Pyrophosphate-Lyase 5 antibody Anti-Adenylate Cyclase Type V antibody Anti-Adenylyl Cyclase 5 antibody Anti-Ac5 antibody Anti-ADCY5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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