5HT1A Blocking Peptide for STJ500001 peptide (STJ503611) STJ503611-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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5HT1A Blocking Peptide for STJ500001 peptide (STJ503611)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	5HT1A Blocking Peptide for STJ500001 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Htr1a
Gene ID:	24473
Uniprot ID:	5HT1A_RAT
Immunogen Region:	200-250
Specificity:	This blocking peptide is recommended for use in combination with 5HT1A antibody, STJ500001
Immunogen:	Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytrptamine receptor 1A protein.

Tissue Specificity	Detected in hypothalamus, mesencephalon, amygdala, medulla, thalamus, septum and hippocampus.
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Peptide Name	5-Hydroxytryptamine Receptor 1a 5-Ht-1a 5-Ht1a Serotonin Receptor 1a
Database Links	Reactome: R-RNO-390666
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cell Projection Dendrite
Alternative Peptide Names	5-Hydroxytryptamine Receptor 1a protein 5-Ht-1a protein 5-Ht1a protein Serotonin Receptor 1a protein Htr1a protein 5ht1a protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：5HT1A Blocking Peptide for STJ500001 peptide (STJ503611)