產品詳情
簡單介紹：
Anti-AADACL1 antibody (C-Term) (STJ71461)
詳情介紹：
| Host: | Goat |
| Applications: | Pep-ELISA/IF/FC |
| Reactivity: | Human/Mouse/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-AADACL1 (C-Term) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | IF-Strong expression of the protein seen in the Endoplasmic reticulum of A431 and U2OS cells. 10µg/ml ELISA-antibody detection limit dilution 1:1000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | NCEH1 |
| Gene ID: | 57552 |
| Uniprot ID: | NCEH1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_065843.3; NP_001139748.2; NP_001139749.1 |
| Immunogen Sequence: | RTRNSYIKWLDQN |
| Post Translational Modifications | N-glycosylated. |
| Function | Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration. |
| Protein Name | Neutral Cholesterol Ester Hydrolase 1 Nceh Acetylalkylglycerol Acetylhydrolase 2-Acetyl Mage Hydrolase Arylacetamide Deacetylase-Like 1 |
| Database Links | Reactome: R-HSA-8964038 |
| Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Microsome |
| Alternative Antibody Names | Anti-Neutral Cholesterol Ester Hydrolase 1 antibody Anti-Nceh antibody Anti-Acetylalkylglycerol Acetylhydrolase antibody Anti-2-Acetyl Mage Hydrolase antibody Anti-Arylacetamide Deacetylase-Like 1 antibody Anti-NCEH1 antibody Anti-AADACL1 antibody Anti-KIAA1363 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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