biotin-SUMO2-VME protein (Recombinant) (No Tag) {Biotin} (STJP002537) STJP002537-25|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

產品名稱：biotin-SUMO2-VME protein (Recombinant) (No Tag) {Biotin} (STJP002537)
產品型號：STJP002537-25
產品廠商：ST john's laboratory
產品文檔：

你添加了1件商品查看購物車

簡單介紹：

biotin-SUMO2-VME protein (Recombinant) (No Tag) {Biotin} (STJP002537)

詳情介紹：

Host:	Synthetic
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-biotin-SUMO2-VME-No Tag protein was developed from synthetic and has a target region of No Tag. For use in research applications.

Conjugation:	Biotin
Formulation:	Lyophilised powder
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	SUMO2
Gene ID:	6613
Uniprot ID:	SUMO2_HUMAN

Post Translational Modifications	Polymeric chains can be formed through Lys-11 cross-linking. Polymeric SUMO2 chains undergo 'Lys-6'-, 'Lys-11'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination by RNF4. Cleavage of precursor form by SENP1 or SENP2 is necessary for function. Monoubiquitinated N-terminally by UBE2W, which primes it for RNF4-dependent polyubiquitination by the UBE2V1-UBE2N heterodimer.
Function	Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. Plays a role in the regulation of sumoylation status of SETX.
Protein Name	Small Ubiquitin-Related Modifier 2 Sumo-2 Hsmt3 Smt3 Homolog 2 Sumo-3 Sentrin-2 Ubiquitin-Like Protein Smt3b Smt3b
Database Links	Reactome: R-HSA-196791 Reactome: R-HSA-3065676 Reactome: R-HSA-3065678 Reactome: R-HSA-3065679 Reactome: R-HSA-3108214 Reactome: R-HSA-3232118 Reactome: R-HSA-3899300 Reactome: R-HSA-4085377 Reactome: R-HSA-4090294 Reactome: R-HSA-4551638 Reactome: R-HSA-4570464 Reactome: R-HSA-4615885 Reactome: R-HSA-5693607 Reactome: R-HSA-5696395
Cellular Localisation	Nucleus Pml Body
Alternative Protein Names	Small Ubiquitin-Related Modifier 2 protein Sumo-2 protein Hsmt3 protein Smt3 Homolog 2 protein Sumo-3 protein Sentrin-2 protein Ubiquitin-Like Protein Smt3b protein Smt3b protein SUMO2 protein SMT3B protein SMT3H2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：biotin-SUMO2-VME protein (Recombinant) (No Tag) {Biotin} (STJP002537)