產品詳情
簡單介紹:
CDNF protein (STJP000138)
詳情介紹:
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | CDNF-protein was developed from. For use in research applications. |
Formulation: | PBS pH 7.4 |
Purification: | Purified by ion-exchange chromatography and gel-filtration from serum-free CHO growth media. Protein is sterile-filtrated through 0.22 µm filter |
Concentration: | 1 mg/ml |
Storage Instruction: | Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
Gene Symbol: | CDNF |
Gene ID: | 441549 |
Uniprot ID: | CDNF_HUMAN |
Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
Protein Name | Cerebral Dopamine Neurotrophic Factor Armet-Like Protein 1 Conserved Dopamine Neurotrophic Factor |
Cellular Localisation | Secreted |
Alternative Protein Names | Cerebral Dopamine Neurotrophic Factor protein Armet-Like Protein 1 protein Conserved Dopamine Neurotrophic Factor protein CDNF protein ARMETL1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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