Anti-ABCB1 antibody (630-710) (STJ29844) STJ29844|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-ABCB1 antibody (630-710) (STJ29844)

詳情介紹：

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-P Glycoprotein (630-710) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCB1
Gene ID:	5243
Uniprot ID:	MDR1_HUMAN
Immunogen Region:	630-710
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 630-710 of human P Glycoprotein (NP_000918.2).
Immunogen Sequence:	TAGNEVELENAADESKSEID ALEMSSNDSRSSLIRKRSTR RSVRGSQAQDRKLSTKEALD ESIPPVSFWRIMKLNLTEWP Y

Tissue Specificity	Expressed in small intestine. Expressed in liver, kidney and brain.
Function	Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Protein Name	Atp-Dependent Translocase Abcb1 Atp-Binding Cassette Sub-Family B Member 1 Multidrug Resistance Protein 1 P-Glycoprotein 1 Phospholipid Transporter Abcb1 Cd Antigen Cd243
Database Links	Reactome: R-HSA-2161517 Reactome: R-HSA-382556 Reactome: R-HSA-9754706 Reactome: R-HSA-9757110
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Cytoplasm Abcb1 Localization Is Influenced By C1orf115 Expression Levels (Plasma Membrane Versus Cytoplasm) Localized To The Apical Membrane Of Enterocytes
Alternative Antibody Names	Anti-Atp-Dependent Translocase Abcb1 antibody Anti-Atp-Binding Cassette Sub-Family B Member 1 antibody Anti-Multidrug Resistance Protein 1 antibody Anti-P-Glycoprotein 1 antibody Anti-Phospholipid Transporter Abcb1 antibody Anti-Cd Antigen Cd243 antibody Anti-ABCB1 antibody Anti-MDR1 antibody Anti-PGY1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ABCB1 antibody (630-710) (STJ29844)