產品詳情
簡單介紹：
Anti-ABCB8 antibody (469-718) (STJ22457)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-ABCB8 (469-718) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:100 IF/ICC 1:50-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABCB8 |
| Gene ID: | 11194 |
| Uniprot ID: | MITOS_HUMAN |
| Immunogen Region: | 469-718 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 469-718 of human ABCB8 (NP_009119.2). |
| Immunogen Sequence: | GFEVLKDFTLTLPPGKIVAL VGQSGGGKTTVASLLERFYD PTAGVVMLDGRDLRTLDPSW LRGQVVGFISQEPVLFGTTI MENIRFGKLEASDEEVYTAA REANAHEFITSFPEGYNTVV GERGTTLSGGQKQRLAIARA LIKQPTVLILDEATSALDAE SERVVQEALDRASAGRTVLV IAHRLSTVRGAHCIVVMADG RVWEAGTHEELLKKGGLYAE LIRRQALDAPRTAAPPPKK |
| Tissue Specificity | Ubiquitous. |
| Function | ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane. Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes. |
| Protein Name | Mitochondrial Potassium Channel Atp-Binding Subunit Atp-Binding Cassette Sub-Family B Member 8 - Mitochondrial Abcb8 Mitochondrial Atp-Binding Cassette 1 M-Abc1 Mitochondrial Sulfonylurea-Receptor Mitosur |
| Database Links | Reactome: R-HSA-1369007 |
| Cellular Localisation | Mitochondrion Inner Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Potassium Channel Atp-Binding Subunit antibody Anti-Atp-Binding Cassette Sub-Family B Member 8 - Mitochondrial antibody Anti-Abcb8 antibody Anti-Mitochondrial Atp-Binding Cassette 1 antibody Anti-M-Abc1 antibody Anti-Mitochondrial Sulfonylurea-Receptor antibody Anti-Mitosur antibody Anti-ABCB8 antibody Anti-MABC1 antibody Anti-MITOSUR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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