產品詳情
簡單介紹:
Anti-ABCB8 antibody (510-590 aa) (STJ190581)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Mitochondrial potassium channel ATP-binding subunit (510-590 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ABCB8 |
Gene ID: | 11194 |
Uniprot ID: | MITOS_HUMAN |
Immunogen Region: | 510-590 aa |
Specificity: | ABCB8 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 510-590 |
Function | ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane. Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes. |
Protein Name | Mitochondrial Potassium Channel Atp-Binding Subunit Atp-Binding Cassette Sub-Family B Member 8 - Mitochondrial Abcb8 Mitochondrial Atp-Binding Cassette 1 M-Abc1 Mitochondrial Sulfonylurea-Receptor Mitosur |
Database Links | Reactome: R-HSA-1369007 |
Cellular Localisation | Mitochondrion Inner Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Mitochondrial Potassium Channel Atp-Binding Subunit antibody Anti-Atp-Binding Cassette Sub-Family B Member 8 - Mitochondrial antibody Anti-Abcb8 antibody Anti-Mitochondrial Atp-Binding Cassette 1 antibody Anti-M-Abc1 antibody Anti-Mitochondrial Sulfonylurea-Receptor antibody Anti-Mitosur antibody Anti-ABCB8 antibody Anti-MABC1 antibody Anti-MITOSUR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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