產品詳情
簡單介紹:
Anti-ABCC2 antibody [M2III-6] (STJ16101427)
詳情介紹:
Host: | Mouse |
Applications: | ICC/IHC-F/IHC-P/FC/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-MRP2 is suitable for use in Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | M2III-6 |
Conjugation: | Unconjugated |
Isotype: | IgG2a |
Formulation: | PBS with 0.1% BSA and 0.02% sodium azide |
Purification: | Protein G purified |
Concentration: | 100 ug/mL |
Dilution Range: | ICC IHC-F 1:20 IHC-P FC WB 1:20-50 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | 202-amino acid COOH terminal end of the protein. |
Background | M2III-6 reacts with an internal epitope of cMOAT/MRP2, a 170-180 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-6 was raised against a bacterial fusion protein of cMOAB/MRP2, containing the 202-amino acid COOH terminal end of the protein. M2III-6 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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