Anti-ABCC3 antibody (830-950) (STJ111891) STJ111891|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-ABCC3 antibody (830-950) (STJ111891)
產品型號：STJ111891
產品廠商：ST john's laboratory
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簡單介紹：

Anti-ABCC3 antibody (830-950) (STJ111891)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ABCC3 (830-950) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCC3
Gene ID:	8714
Uniprot ID:	MRP3_HUMAN
Immunogen Region:	830-950
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 830-950 of human ABCC3 (NP_003777.2).
Immunogen Sequence:	SEMGPYPALLQRNGSFANFL CNYAPDEDQGHLEDSWTALE GAEDKEALLIEDTLSNHTDL TDNDPVTYVVQKQFMRQLSA LSSDGEGQGRPVPRRHLGPS EKVQVTEAKADGALTQEEKA A

Tissue Specificity	Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney. In testis, localized to peritubular myoid cells, Leydig cells, along the basal membrane of Sertoli cells and moderately in the adluminal compartment of the seminiferous tubules.
Function	ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports glucuronide conjugates such as bilirubin diglucuronide, estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). Transports also various bile salts (taurocholate, glycocholate, taurochenodeoxycholate-3-sulfate, taurolithocholate- 3-sulfate). Does not contribute substantially to bile salt physiology but provides an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Can confer resistance to various anticancer drugs, methotrexate, tenoposide and etoposide, by decreasing accumulation of these drugs in cells.
Protein Name	Atp-Binding Cassette Sub-Family C Member 3 Canalicular Multispecific Organic Anion Transporter 2 Multi-Specific Organic Anion Transporter D Moat-D Multidrug Resistance-Associated Protein 3
Database Links	Reactome: R-HSA-159418 Reactome: R-HSA-382556 Reactome: R-HSA-9749641 Reactome: R-HSA-9753281
Cellular Localisation	Basolateral Cell Membrane Multi-Pass Membrane Protein Basal Cell Membrane Localized To The Basolateral Membrane Of Enterocytes Localized To The Basal Membrane Of Sertoli Cells
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family C Member 3 antibody Anti-Canalicular Multispecific Organic Anion Transporter 2 antibody Anti-Multi-Specific Organic Anion Transporter D antibody Anti-Moat-D antibody Anti-Multidrug Resistance-Associated Protein 3 antibody Anti-ABCC3 antibody Anti-CMOAT2 antibody Anti-MLP2 antibody Anti-MRP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ABCC3 antibody (830-950) (STJ111891)