產品詳情
簡單介紹:
GFRA-2 protein (STJP000150)
詳情介紹:
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | GFRA-2-protein was developed from. For use in research applications. |
Formulation: | PBS pH 7.4 |
Concentration: | 0.7 mg/ml |
Storage Instruction: | Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
Gene Symbol: | GFRA2 |
Gene ID: | 2675 |
Uniprot ID: | GFRA2_HUMAN |
Tissue Specificity | Isoform 1 is found in both brain and placenta. |
Function | Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Isoform 2: Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3. |
Protein Name | Gdnf Family Receptor Alpha-2 Gdnf Receptor Alpha-2 Gdnfr-Alpha-2 Gfr-Alpha-2 Gdnf Receptor Beta Gdnfr-Beta Neurturin Receptor Alpha Nrtnr-Alpha Ntnr-Alpha Ret Ligand 2 Tgf-Beta-Related Neurotrophic Factor Receptor 2 |
Database Links | Reactome: R-HSA-419037 Reactome: R-HSA-5673001 Reactome: R-HSA-8853659 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
Alternative Protein Names | Gdnf Family Receptor Alpha-2 protein Gdnf Receptor Alpha-2 protein Gdnfr-Alpha-2 protein Gfr-Alpha-2 protein Gdnf Receptor Beta protein Gdnfr-Beta protein Neurturin Receptor Alpha protein Nrtnr-Alpha protein Ntnr-Alpha protein Ret Ligand 2 protein Tgf-Beta-Related Neurotrophic Factor Receptor 2 protein GFRA2 protein GDNFRB protein RETL2 protein TRNR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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