ARF1 Blocking Peptide for STJ500153 peptide (STJ503683) STJ503683-250|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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ARF1 Blocking Peptide for STJ500153 peptide (STJ503683)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	ARF1 Blocking Peptide for STJ500153 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Arf1
Gene ID:	64310
Uniprot ID:	ARF1_RAT
Specificity:	This blocking peptide is recommended for use in combination with ARF1 antibody, STJ500153
Immunogen:	Synthetic peptide corresponding to unique amino acid sequence on Rat ARF1 protein. The peptide was covalently modified post-synthetically to achieve desied antigenicity.

Function	Small GTPase involved in protein trafficking between different compartments. Modulates vesicle budding and uncoating within the Golgi complex. In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity.the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasticity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Peptide Name	Adp-Ribosylation Factor 1
Database Links	Reactome: R-RNO-1660499 Reactome: -RNO-1660514 Reactome: -RNO-199992 Reactome: -RNO-2132295 Reactome: -RNO-432720 Reactome: -RNO-432722 Reactome: -RNO-6807878 Reactome: -RNO-6811434 Reactome: -RNO-6811438
Cellular Localisation	Golgi Apparatus Membrane Lipid-Anchor Cytoplasmic Side Synapse Synaptosome Postsynaptic Density In The Gdp-Bound Form Associates Transiently With The Membranes Via Its Myristoylated N-Terminus Where Guanine Nucleotide-Exchange Factor (Gef)-Mediated Nucleotide Exchange Occurs Following Nucleotide Exchange The Gtp-Bound Form Undergoes A Conformational Change Leading To The Exposure Of A Myristoylated N-Terminal Amphipathic Helix That Provides Stable Membrane Anchorage
Alternative Peptide Names	Adp-Ribosylation Factor 1 protein Arf1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：ARF1 Blocking Peptide for STJ500153 peptide (STJ503683)