產品詳情
簡單介紹:
ASIC2 Blocking Peptide for STJ500176 peptide (STJ505573)
詳情介紹:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | ASIC2 Blocking Peptide for STJ500176 is synthetically produced from the 450-512 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | ASIC2 |
Gene ID: | 40 |
Uniprot ID: | ASIC2_HUMAN |
Immunogen Region: | 450-512 |
Specificity: | This blocking peptide is recommended for use in combination with ASIC2 antibody, STJ500176 |
Immunogen: | Synthetic peptide taken within amino acid region 450-512 on human Acid-sensing ion channel 2 protein. |
Tissue Specificity | Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary. |
Function | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. |
Peptide Name | Acid-Sensing Ion Channel 2 Asic2 Amiloride-Sensitive Brain Sodium Channel Amiloride-Sensitive Cation Channel 1 - Neuronal Amiloride-Sensitive Cation Channel Neuronal 1 Brain Sodium Channel 1 Bnc1 Bnac1 Mammalian Degenerin Homolog Mdeg |
Database Links | Reactome: R-HSA-2672351 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Localized At The Plasma Membrane Of Neurons In The Soma And Punctated Peripheral Processes |
Alternative Peptide Names | Acid-Sensing Ion Channel 2 protein Asic2 protein Amiloride-Sensitive Brain Sodium Channel protein Amiloride-Sensitive Cation Channel 1 - Neuronal protein Amiloride-Sensitive Cation Channel Neuronal 1 protein Brain Sodium Channel 1 protein Bnc1 protein Bnac1 protein Mammalian Degenerin Homolog protein Mdeg protein ASIC2 protein ACCN protein ACCN1 protein BNAC1 protein MDEG protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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