ASXL1 Positive Control for STJ506153 peptide (STJ505858) STJ505858-5|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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ASXL1 Positive Control for STJ506153 peptide (STJ505858)

詳情介紹：

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	ASXL1 Positive Control for STJ506153 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Asxl1
Gene ID:	228790
Uniprot ID:	ASXL1_MOUSE
Specificity:	This is positive control is recommended for use in combination with ASXL1 antibody STJ506153.

Post Translational Modifications	Ubiquitinated by TRIP12, leading to its subsequent degradation following binding N(6)-methyladenosine methylated DNA (m6A).
Function	Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as a coactivator of RARA and RXRA through association with NCOA1. Acts as a corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its ubiquitination and degradation by TRIP12, thereby inactivating the PR-DUB complex and regulating Polycomb silencing.
Peptide Name	Polycomb Group Protein Asxl1 Additional Sex Combs-Like Protein 1
Database Links	Reactome: R-MMU-5689603
Cellular Localisation	Nucleus
Alternative Peptide Names	Polycomb Group Protein Asxl1 protein Additional Sex Combs-Like Protein 1 protein Asxl1 protein Kiaa0978 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：ASXL1 Positive Control for STJ506153 peptide (STJ505858)