Anti-ABCC4/MRP4 antibody (C-Term) (STJ70611) STJ70611-100|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-ABCC4/MRP4 antibody (C-Term) (STJ70611)
產品型號：STJ70611-100
產品廠商：ST john's laboratory
產品文檔：

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簡單介紹：

Anti-ABCC4/MRP4 antibody (C-Term) (STJ70611)

詳情介紹：

Host:	Goat
Applications:	Pep-ELISA/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-ABCC4/MRP4 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	IHC-Recommended concentration, 4-6µg/ml ELISA-antibody detection limit dilution 1:32000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ABCC4
Gene ID:	10257
Uniprot ID:	MRP4_HUMAN
Immunogen Region:	C-Term
Accession Number:	NP_005836.2
Specificity:	This antibody is expected to recognize isoform 1 (NP_005836.2) only.
Immunogen Sequence:	CNGQPSTLTIFETAL

Post Translational Modifications	N-glycosylated.leading to substrate-selective effects on its transport activity.
Function	ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotics molecules. Confers resistance to anticancer agents such as methotrexate.
Protein Name	Atp-Binding Cassette Sub-Family C Member 4 Mrp/Cmoat-Related Abc Transporter Multi-Specific Organic Anion Transporter B Moat-B Multidrug Resistance-Associated Protein 4
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-382556 Reactome: R-HSA-9748787 Reactome: R-HSA-9753281
Cellular Localisation	Basolateral Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Its Localization To The Basolateral Or Apical Membranes Is Tissue-Dependent
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family C Member 4 antibody Anti-Mrp/Cmoat-Related Abc Transporter antibody Anti-Multi-Specific Organic Anion Transporter B antibody Anti-Moat-B antibody Anti-Multidrug Resistance-Associated Protein 4 antibody Anti-ABCC4 antibody Anti-MOATB antibody Anti-MRP4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ABCC4/MRP4 antibody (C-Term) (STJ70611)