Anti-ABCD2 antibody (460-473) (STJ72794) STJ72794-100|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-ABCD2 antibody (460-473) (STJ72794)

詳情介紹：

Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-ABCD2 (460-473) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.5-2µg/ml ELISA-antibody detection limit dilution 1:32000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ABCD2
Gene ID:	225
Uniprot ID:	ABCD2_HUMAN
Immunogen Region:	460-473
Accession Number:	NP_005155.1
Specificity:	No cross-reactivity expected with ABCD1.
Immunogen Sequence:	PLSDTLAIKGKVID

Function	ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen. Like ABCD1 seems to have fatty acyl-CoA thioesterase (ACOT) and ATPase activities, according to this model, VLCFA-CoA as free VLCFA is transpoted in an ATP-dependent manner into peroxisomes after the hydrolysis of VLCFA-CoA mediated by the ACOT activity of ABCD2 (Probable). Shows overlapping substrate specificities with ABCD1 toward saturated fatty acids (FA) and monounsaturated FA (MUFA) but has a distinct substrate preference for shorter VLCFA (C22:0) and polyunsaturated fatty acid (PUFA) such as C22:6-CoA and C24:6-CoA (in vitro). Thus, may play a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosesynthesis of fatty acids by beta-oxidation.
Protein Name	Atp-Binding Cassette Sub-Family D Member 2 Adrenoleukodystrophy-Like 1 Adrenoleukodystrophy-Related Protein Haldr
Database Links	Reactome: R-HSA-1369062 Reactome: R-HSA-9603798
Cellular Localisation	Peroxisome Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family D Member 2 antibody Anti-Adrenoleukodystrophy-Like 1 antibody Anti-Adrenoleukodystrophy-Related Protein antibody Anti-Haldr antibody Anti-ABCD2 antibody Anti-ALD1 antibody Anti-ALDL1 antibody Anti-ALDR antibody Anti-ALDRP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ABCD2 antibody (460-473) (STJ72794)