產品詳情
簡單介紹:
Anti-ABCD4 antibody (Internal) (STJ71634)
詳情介紹:
Host: | Goat |
Applications: | Pep-ELISA/WB/IHC |
Reactivity: | Human/Mouse/Rat/Dog |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-ABCD4 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.3-1µg/ml IHC-3.75µg/ml ELISA-antibody detection limit dilution 1:8000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | ABCD4 |
Gene ID: | 5826 |
Uniprot ID: | ABCD4_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_005041.1 |
Specificity: | Reported variants represent identical protein: NP_064719.1 NP_064731.1 NP_064720.1 NP_064730.1 |
Immunogen Sequence: | RDDIDNPDQRISQD |
Function | Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane. |
Protein Name | Lysosomal Cobalamin Transporter Abcd4 Atp-Binding Cassette Sub-Family D Member 4 Pmp70-Related Protein P70r Peroxisomal Membrane Protein 1-Like Pxmp1-L Peroxisomal Membrane Protein 69 Pmp69 |
Database Links | Reactome: R-HSA-5683329 Reactome: R-HSA-9758881 Reactome: R-HSA-9758890 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Lysosome Membrane Targeted By Lmbrd1 Lysosomal Chaperone To The Lysosomal Membrane |
Alternative Antibody Names | Anti-Lysosomal Cobalamin Transporter Abcd4 antibody Anti-Atp-Binding Cassette Sub-Family D Member 4 antibody Anti-Pmp70-Related Protein antibody Anti-P70r antibody Anti-Peroxisomal Membrane Protein 1-Like antibody Anti-Pxmp1-L antibody Anti-Peroxisomal Membrane Protein 69 antibody Anti-Pmp69 antibody Anti-ABCD4 antibody Anti-PXMP1L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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