Human ALK-1/ACVRL1 protein (Recombinant) (C-His) (STJP001078) STJP001078|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human ALK-1/ACVRL1 protein (Recombinant) (C-His) (STJP001078)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human ALK-1/ACVRL1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Endotoxin:	Please contact us for more information.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Human ALK-1 at 4 Mu g/mL (100 Mu L/well) can bind Human ACVR2B with a linear range of 0.08-2.4 Mu g/mL.

Gene Symbol:	ACVRL1
Gene ID:	94
Uniprot ID:	ACVL1_HUMAN
Immunogen:	Recombinant Human ALK-1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp22-Gln118) of human ALK-1 (Accession #NP_000011.2) fused with a 6×His tag at the C-terminus.

Function	Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Protein Name	Serine/Threonine-Protein Kinase Receptor R3 Skr3 Activin Receptor-Like Kinase 1 Alk-1 Tgf-B Superfamily Receptor Type I Tsr-I
Database Links	Reactome: R-HSA-201451
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Serine/Threonine-Protein Kinase Receptor R3 protein Skr3 protein Activin Receptor-Like Kinase 1 protein Alk-1 protein Tgf-B Superfamily Receptor Type I protein Tsr-I protein ACVRL1 protein ACVRLK1 protein ALK1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human ALK-1/ACVRL1 protein (Recombinant) (C-His) (STJP001078)