產品詳情
簡單介紹:
Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human ALK-7/ACVR1C-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: | ACVR1C |
Gene ID: | 130399 |
Uniprot ID: | ACV1C_HUMAN |
Immunogen: | Recombinant Human ALK-7/ACVR1C Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu22-Glu113) of human ALK-7 Protein (Accession #NP_660302.2) fused with an Fc, 6×His tag at the C-terminus. |
Function | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. |
Protein Name | Activin Receptor Type-1c Activin Receptor Type Ic Actr-Ic Activin Receptor-Like Kinase 7 Alk-7 |
Database Links | Reactome: R-HSA-1181150 Reactome: R-HSA-1433617 Reactome: R-HSA-1502540 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Activin Receptor Type-1c protein Activin Receptor Type Ic protein Actr-Ic protein Activin Receptor-Like Kinase 7 protein Alk-7 protein ACVR1C protein ALK7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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