Human alpha 1 antichymotrypsin protein (Recombinant) (STJP000305) STJP000305|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Human alpha 1 antichymotrypsin protein (Recombinant) (STJP000305)

詳情介紹：

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human alpha 1 antichymotrypsin-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Dilution Range:	Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:	The activity was measured by the ability of inhibit chymotrypsin cleavage of a fluorogenic peptide substrate, and the calulated ED50 was found to be < 6nM NA

Gene Symbol:	SERPINA3
Gene ID:	12
Uniprot ID:	AACT_HUMAN
Immunogen Region:	HIS23-ALA423
Immunogen:	Optimized DNA sequence encodingHuman alpha 1 antichymotrypsin-AACT (HIS23-ALA423) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA

Tissue Specificity	Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.
Post Translational Modifications	N- and O-glycosylated.
Function	Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Protein Name	Alpha-1-Antichymotrypsin Act Cell Growth-Inhibiting Gene 24/25 Protein Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-6798695
Cellular Localisation	Secreted
Alternative Protein Names	Alpha-1-Antichymotrypsin protein Act protein Cell Growth-Inhibiting Gene 24/25 Protein protein Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less protein SERPINA3 protein AACT protein GIG24 protein GIG25 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human alpha 1 antichymotrypsin protein (Recombinant) (STJP000305)