產品詳情
簡單介紹:
Human Alpha-fetoprotein/AFP protein (Recombinant) (C-His) (STJP001012)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Alpha-fetoprotein/AFP-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human AFP at 2 Mu g/mL (100 Mu L/well) can bind AFP Mouse mAb with a linear range of 0.061-5.431 ng/mL. |
Gene Symbol: | AFP |
Gene ID: | 174 |
Uniprot ID: | FETA_HUMAN |
Immunogen: | Recombinant Human Alpha-fetoprotein/AFP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg19-Val609) of human Alpha-fetoprotein (Accession #NP_001125.1) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
Protein Name | Alpha-Fetoprotein Alpha-1-Fetoprotein Alpha-Fetoglobulin |
Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Protein Names | Alpha-Fetoprotein Alpha-1-Fetoprotein Alpha-Fetoglobulin protein AFP protein HPAFP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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