Human Azurocidin/CAP37/AZU1 protein (Recombinant) (C-His) (STJP000969) STJP000969|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Human Azurocidin/CAP37/AZU1 protein (Recombinant) (C-His) (STJP000969)
產品型號：STJP000969
產品廠商：ST john's laboratory
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簡單介紹：

Human Azurocidin/CAP37/AZU1 protein (Recombinant) (C-His) (STJP000969)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Azurocidin/CAP37/AZU1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:

Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.

Gene Symbol:	AZU1
Gene ID:	566
Uniprot ID:	CAP7_HUMAN
Immunogen:	Recombinant Human Azurocidin/CAP37/AZU1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ile27-Pro250) of human AZU1/Azurocidin 1/CAP37 (Accession #NP_001691.1) fused with a 6×His tag at the C-term

Post Translational Modifications	Cleavage of the N-terminal propeptide which is composed of 7 amino acids occurs in two steps. The initial cleavage of 5 amino acids is followed by the cleavage of a dipeptide to produce the mature form.
Function	This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
Protein Name	Azurocidin Cationic Antimicrobial Protein Cap37 Heparin-Binding Protein Hbp Hhbp
Database Links	Reactome: R-HSA-6798695
Cellular Localisation	Cytoplasmic Granule Membrane Peripheral Membrane Protein Cytoplasmic Side Localizes To Azurophil Granules Of Neutrophil Granulocytes Also Called Primary Granules These Specialized Lysosomes Of The Neutrophil Formed Early During Promyelocyte Development Store Antibacterial Proteins And Peptides
Alternative Protein Names	Azurocidin protein Cationic Antimicrobial Protein Cap37 protein Heparin-Binding Protein protein Hbp protein Hhbp protein AZU1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Human Azurocidin/CAP37/AZU1 protein (Recombinant) (C-His) (STJP000969)