產品詳情
簡單介紹:
Human Carboxypeptidase E protein (Recombinant) (STJP000454)
詳情介紹:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Carboxypeptidase E-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The activity was tested by the ability to cleave a peptide substrate, benzoylAROH, and was measured to be 10 nMole/min/ug. NA |
Gene Symbol: | CPE |
Gene ID: | 1363 |
Uniprot ID: | CBPE_HUMAN |
Immunogen Region: | GLU26-SER453 |
Immunogen: | Optimized DNA sequence encoding peptidase domain of Human Carboxypeptidase E-CPE (GLU26-SER453 ) including a C-terminal His tag was expressed in HEK293 cells. NA |
Function | Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage. |
Protein Name | Carboxypeptidase E Cpe Carboxypeptidase H Cph Enkephalin Convertase Prohormone-Processing Carboxypeptidase |
Database Links | Reactome: R-HSA-264876 |
Cellular Localisation | Isoform 1: Cytoplasmic Vesicle Secretory Vesicle Cytoplasmic Vesicle Secretory Vesicle Membrane Peripheral Membrane Protein Secreted Associated With The Secretory Granule Membrane Through Direct Binding To Lipid Rafts In Intragranular Conditions |
Alternative Protein Names | Carboxypeptidase E protein Cpe protein Carboxypeptidase H protein Cph protein Enkephalin Convertase protein Prohormone-Processing Carboxypeptidase protein CPE protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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