產品詳情
簡單介紹:
Human Cathepsin D protein (Recombinant) (STJP000376)
詳情介紹:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Cathepsin D-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The activity was tested by the ability to cleave a flourogenic substrate, the measured activity is 0.5 nmole/ug/min NA |
Gene Symbol: | CTSS |
Gene ID: | 1520 |
Uniprot ID: | CATS_HUMAN |
Immunogen Region: | SER19-LEU412 |
Immunogen: | Optimized DNA sequence encoding mature chain of human Cathepsin D-CatD (SER19-LEU412) including a C-terminal His tag was expressed in HEK293 cells. NA |
Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
Protein Name | Cathepsin S |
Database Links | Reactome: R-HSA-1236977 Reactome: R-HSA-1474228 Reactome: R-HSA-1679131 Reactome: R-HSA-2022090 Reactome: R-HSA-2132295 Reactome: R-HSA-6798695 |
Cellular Localisation | Lysosome Secreted Cytoplasmic Vesicle Phagosome |
Alternative Protein Names | Cathepsin S protein CTSS protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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