產品詳情
簡單介紹:
CACNB2 Blocking Peptide for STJ500387 peptide (STJ503778)
詳情介紹:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | CACNB2 Blocking Peptide for STJ500387 is synthetically produced from the 500-600 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | Cacnb2 |
Gene ID: | 116600 |
Uniprot ID: | CACB2_RAT |
Immunogen Region: | 500-600 |
Specificity: | This blocking peptide is recommended for use in combination with CACNB2 antibody, STJ500387 |
Immunogen: | Synthetic peptide taken within amino acid region 500-600 on rat voltage-dependent L-type calcium channel subunit beta-2 protein |
Tissue Specificity | Highly expressed in heart and brain, and at lower levels in lung. |
Post Translational Modifications | Regulated through phosphorylation at Thr-549 by CaMK2D. |
Function | Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C. |
Peptide Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 Cab2 Calcium Channel Voltage-Dependent Subunit Beta 2 |
Database Links | Reactome: R-RNO-112308 Reactome: -RNO-422356 Reactome: -RNO-5576892 Reactome: -RNO-5576893 |
Cellular Localisation | Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side |
Alternative Peptide Names | Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 protein Cab2 protein Calcium Channel Voltage-Dependent Subunit Beta 2 protein Cacnb2 protein Cacnlb2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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