Anti-ACADM antibody (200-300) [S5MR] (STJ11102105) STJ11102105|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-ACADM antibody (200-300) [S5MR] (STJ11102105)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-ACADM (200-300) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S5MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ACADM
Gene ID:	34
Uniprot ID:	ACADM_HUMAN
Immunogen Region:	200-300
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ACADM (P11310).
Immunogen Sequence:	WYFLLARSDPDPKAPANKAF TGFIVEADTPGIQIGRKELN MGQRCSDTRGIVFEDVKVPK ENVLIGDGAGFKVAMGAFDK TRPVVAAGAVGLAQRALDEA T

Post Translational Modifications	Acetylated. Could occur at proximity of the cofactor-binding sites and reduce the catalytic activity. Could be deacetylated by SIRT3.
Function	Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains.
Protein Name	Medium-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial Mcad Medium Chain Acyl-Coa Dehydrogenase Mcadh
Database Links	Reactome: R-HSA-1989781 Reactome: R-HSA-77288 Reactome: R-HSA-77346 Reactome: R-HSA-77348
Cellular Localisation	Mitochondrion Matrix
Alternative Antibody Names	Anti-Medium-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody Anti-Mcad antibody Anti-Medium Chain Acyl-Coa Dehydrogenase antibody Anti-Mcadh antibody Anti-ACADM antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ACADM antibody (200-300) [S5MR] (STJ11102105)