產品詳情
簡單介紹：
Anti-ACADSB antibody (133-432) (STJ117213)
詳情介紹：
| Host: | Rabbit |
| Applications: | IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-ACADSB (133-432) is suitable for use in Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | IHC-P 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACADSB |
| Gene ID: | 36 |
| Uniprot ID: | ACDSB_HUMAN |
| Immunogen Region: | 133-432 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 133-432 of human ACADSB (NP_001600.1). |
| Immunogen Sequence: | ASVAVFCEIQNTLINTLIRK HGTEEQKATYLPQLTTEKVG SFCLSEAGAGSDSFALKTRA DKEGDYYVLNGSKMWISSAE HAGLFLVMANVDPTIGYKGI TSFLVDRDTPGLHIGKPENK LGLRASSTCPLTFENVKVPE ANILGQIGHGYKYAIGSLNE GRIGIAAQMLGLAQGCFDYT IPYIKERIQFGKRLFDFQGL QHQVAHVATQLEAARLLTYN AARLLEAGKPFIKEASMAK |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug. |
| Protein Name | Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial Sbcad 2-Methyl Branched Chain Acyl-Coa Dehydrogenase 2-Mebcad 2-Methylbutyryl-Coenzyme A Dehydrogenase 2-Methylbutyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-70895 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody Anti-Sbcad antibody Anti-2-Methyl Branched Chain Acyl-Coa Dehydrogenase antibody Anti-2-Mebcad antibody Anti-2-Methylbutyryl-Coenzyme A Dehydrogenase antibody Anti-2-Methylbutyryl-Coa Dehydrogenase antibody Anti-ACADSB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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