Anti-ACC1 antibody (2100-2200) (STJ11103214) STJ11103214|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-ACC1 antibody (2100-2200) (STJ11103214)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ACC1 (2100-2200) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ACACA
Gene ID:	31
Uniprot ID:	ACACA_HUMAN
Immunogen Region:	2100-2200
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 2100-2200 of human ACACA (NP_942133.1).
Immunogen Sequence:	INPRHMEMYADRESRGSVLE PEGTVEIKFRRKDLVKTMRR VDPVYIHLAERLGTPELSTA ERKELENKLKEREEFLIPIY HQVAVQFADLHDTPGRMQEK G

Tissue Specificity	Expressed in brain, placenta, skeletal muscle, renal, pancreatic and adipose tissues.expressed at low level in pulmonary tissue.not detected in the liver.
Post Translational Modifications	Phosphorylation on Ser-1263 is required for interaction with BRCA1. Phosphorylation at Ser-80 by AMPK inactivates enzyme activity. The biotin cofactor is covalently attached to the central biotinyl-binding domain and is required for the catalytic activity.
Function	Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosesynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
Protein Name	Acetyl-Coa Carboxylase 1 Acc1 Acetyl-Coenzyme A Carboxylase Alpha Acc-Alpha
Database Links	Reactome: R-HSA-163765 Reactome: R-HSA-196780 Reactome: R-HSA-200425 Reactome: R-HSA-2426168 Reactome: R-HSA-3371599 Reactome: R-HSA-75105
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Acetyl-Coa Carboxylase 1 antibody Anti-Acc1 antibody Anti-Acetyl-Coenzyme A Carboxylase Alpha antibody Anti-Acc-Alpha antibody Anti-ACACA antibody Anti-ACAC antibody Anti-ACC1 antibody Anti-ACCA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ACC1 antibody (2100-2200) (STJ11103214)