產品詳情
簡單介紹：
Anti-Acacb-Mouse antibody (Internal) (STJ72669)
詳情介紹：
| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Mouse/Rat/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-Acacb-Mouse (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | IHC-5µg/ml ELISA-antibody detection limit dilution 1:16000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Immunogen Region: | Internal |
| Accession Number: | NP_598665.2 |
| Immunogen Sequence: | TLNVQESGRVKYIKR |
| Function | Mitochondrial enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA and plays a central role in fatty acid metabolism. Catalyzes a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. Through the production of malonyl-CoA that allosterically inhibits carnitine palmitoyltransferase 1 at the mitochondria, negatively regulates fatty acid oxidation. Together with its cytosolic isozyme ACACA, which is involved in de novo fatty acid biosesynthesis, promotes lipid storage. |
| Protein Name | Acetyl-Coa Carboxylase 2 Acc-Beta |
| Database Links | Reactome: R-MMU-163765 Reactome: -MMU-196780 Reactome: -MMU-200425 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Acetyl-Coa Carboxylase 2 antibody Anti-Acc-Beta antibody Anti-Acacb antibody Anti-Acc2 antibody Anti-Accb antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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