產品詳情
簡單介紹:
Anti-ACAP1 antibody (490-570) (STJA0010088)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (490-570) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:1000-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ACAP1 |
Gene ID: | 9744 |
Uniprot ID: | ACAP1_HUMAN |
Immunogen Region: | 490-570 |
Specificity: | This antibody detects endogenous levels of Human Centaurin-Beta 1 |
Immunogen: | Synthesized peptide derived from human Centaurin-Beta 1 AA range: 490-570 |
Tissue Specificity | Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas. |
Post Translational Modifications | Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. |
Function | GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. |
Protein Name | Arf-Gap With Coiled-Coil - Ank Repeat And Ph Domain-Containing Protein 1 Centaurin-Beta-1 Cnt-B1 |
Cellular Localisation | Recycling Endosome Membrane Peripheral Membrane Protein Cytoplasmic Side |
Alternative Antibody Names | Anti-Arf-Gap With Coiled-Coil - Ank Repeat And Ph Domain-Containing Protein 1 antibody Anti-Centaurin-Beta-1 antibody Anti-Cnt-B1 antibody Anti-ACAP1 antibody Anti-CENTB1 antibody Anti-KIAA0050 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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