產品詳情
簡單介紹：
Anti-A4GALT antibody (244-353) (STJ111431)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-A4GALT (244-353) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | A4GALT |
| Gene ID: | 53947 |
| Uniprot ID: | A4GAT_HUMAN |
| Immunogen Region: | 244-353 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-353 of human A4GALT (NP_059132.1). |
| Immunogen Sequence: | WIWGHQGPQLLTRVFKKWCS IRSLAESRACRGVTTLPPEA FYPIPWQDWKKYFEDINPEE LPRLLSATYAVHVWNKKSQG TRFEATSRALLAQLHARYCP TTHEAMKMYL |
| Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
| Function | Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(11')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P. (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins. |
| Protein Name | Lactosylceramide 4-Alpha-Galactosyltransferase Alpha-1 -4-N-Acetylglucosaminyltransferase Alpha-1 -4-Galactosyltransferase Alpha4gal-T1 Cd77 Synthase Globotriaosylceramide Synthase Gb3 Synthase P1/Pk Synthase Udp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase |
| Cellular Localisation | Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide 4-Alpha-Galactosyltransferase antibody Anti-Alpha-1 -4-N-Acetylglucosaminyltransferase antibody Anti-Alpha-1 -4-Galactosyltransferase antibody Anti-Alpha4gal-T1 antibody Anti-Cd77 Synthase antibody Anti-Globotriaosylceramide Synthase antibody Anti-Gb3 Synthase antibody Anti-P1/Pk Synthase antibody Anti-Udp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase antibody Anti-A4GALT antibody Anti-A14GALT antibody Anti-A4GALT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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