产品详情
简单介绍:
Anti-ACADM, Biotinylated antibody (C-Term) {Biotin} (STJ73260)
详情介绍:
Host: | Goat |
Applications: | Pep-ELISA/WB/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-ACADM, Biotinylated (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Biotin |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-2-4µg/ml ELISA-antibody detection limit dilution 1:16000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | ACADM |
Gene ID: | 34 |
Uniprot ID: | ACADM_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_000007.1; NP_001120800.1; NP_001272971.1; NP_001272972.1; NP_001272973.1 |
Specificity: | This antibody is expected to recognise both reported isoforms (NP_000007.1; NP_001120800.1). |
Immunogen Sequence: | RLIVAREHIDKYKN. |
Function | Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains. |
Protein Name | Medium-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial Mcad Medium Chain Acyl-Coa Dehydrogenase Mcadh |
Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-77288 Reactome: R-HSA-77346 Reactome: R-HSA-77348 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Medium-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody Anti-Mcad antibody Anti-Medium Chain Acyl-Coa Dehydrogenase antibody Anti-Mcadh antibody Anti-ACADM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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