产品详情
简单介绍:
Anti-ADGRF5 antibody (22-280) (STJ27181)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ADGRF5 (22-280) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADGRF5 |
Gene ID: | 221395 |
Uniprot ID: | AGRF5_HUMAN |
Immunogen Region: | 22-280 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-280 of human ADGRF5 (NP_056049.4). |
Immunogen Sequence: | ALNWNYESTIHPLSLHEHEP AGEEALRQKRAVATKSPTAE EYTVNIEISFENASFLDPIK AYLNSLSFPIHGNNTDQITD ILSINVTTVCRPAGNEIWCS CETGYGWPRERCLHNLICQE RDVFLPGHHCSCLKELPPNG PFCLLQEDVTLNMRVRLNVG FQEDLMNTSSALYRSYKTDL ETAFRKGYGILPGFKGVTVT GFKSGSVVVTYEVKTTPPSL ELIHKANEQVVQSLNQTYK |
Post Translational Modifications | Proteolytically cleaved at multiple sites: one in the GPS domain (S1 site) and the other in the SEA domain (S2 site). The proteolytic cleavage at S1 site generates an extracellular subunit and a seven-transmembrane subunit. The proteolytic cleavage at S2 site generates a fragment that undergoes proteolytic cleavage by the processing enzyme furin. Highly glycosylated. |
Function | Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. |
Protein Name | Adhesion G Protein-Coupled Receptor F5 G-Protein Coupled Receptor 116 |
Database Links | Reactome: R-HSA-5683826 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor F5 antibody Anti-G-Protein Coupled Receptor 116 antibody Anti-ADGRF5 antibody Anti-GPR116 antibody Anti-KIAA0758 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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