产品详情

  • 产品名称：Anti-ADI1 antibody (71-120 aa) (STJ98823)

  • 产品型号：STJ98823
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ADI1 antibody (71-120 aa) (STJ98823)
详情介绍：
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Acireductone dioxygenase-requiring-requiring (71-120 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
ELISA 1:10000-20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADI1
Gene ID: 55256
Uniprot ID: MTND_HUMAN
Immunogen Region: 71-120 aa
Specificity: The antibody detects endogenous ADI1
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ADI1 at the amino acid range 71-120
Function Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
Protein Name Acireductone Dioxygenase
Acireductone Dioxygenase
Fe(2+-Requiring
Ard'
Fe-Ard
Acireductone Dioxygenase
Ni(2+-Requiring
Ard
Ni-Ard
Membrane-Type 1 Matrix Metalloproteinase Cytoplasmic Tail-Binding Protein 1
Mtcbp-1
Submergence-Induced Protein-Like Factor
Sip-L
Database Links Reactome: R-HSA-1237112
Cellular Localisation Cytoplasm
Nucleus
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Localizes To The Plasma Membrane When Complexed To Mmp14
Alternative Antibody Names Anti-Acireductone Dioxygenase antibody
Anti-Acireductone Dioxygenase antibody
Anti-Fe(2+-Requiring antibody
Anti-Ard' antibody
Anti-Fe-Ard antibody
Anti-Acireductone Dioxygenase antibody
Anti-Ni(2+-Requiring antibody
Anti-Ard antibody
Anti-Ni-Ard antibody
Anti-Membrane-Type 1 Matrix Metalloproteinase Cytoplasmic Tail-Binding Protein 1 antibody
Anti-Mtcbp-1 antibody
Anti-Submergence-Induced Protein-Like Factor antibody
Anti-Sip-L antibody
Anti-ADI1 antibody
Anti-MTCBP1 antibody
Anti-HMFT1638 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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